منابع مشابه
Environmental Risk and Meningitis Epidemics in Africa
of meningococcal meningitis occur in areas with particular environmental characteristics. We present evidence that the relationship between the environment and the location of these epidemics is quantifiable and propose a model based on environmental variables to identify regions at risk for meningitis epidemics. These findings, which have substantial implications for directing surveillance act...
متن کاملCorticosteroids for bacterial meningitis in adults in sub-Saharan Africa.
BACKGROUND In sub-Saharan Africa, bacterial meningitis is common and is associated with a high mortality. Adjuvant therapy with corticosteroids reduces mortality among adults in the developed world, but it has not been adequately tested in developing countries or in the context of advanced human immunodeficiency virus (HIV) infection. METHODS We conducted a randomized, double-blind, placebo-c...
متن کاملEvaluation of the meningitis epidemics risk model in Africa.
Meningitis epidemics have a strong environmental component in Africa with the most severe epidemics occurring in the Sahelian region known as the Meningitis Belt. The objective of this study is to evaluate an ecological model based on absolute humidity and land cover type to predict the location of these epidemics. The risk model is evaluated prospectively based on epidemics occurring in Africa...
متن کاملTreatment of Cryptococcal Meningitis in KwaZulu-Natal, South Africa
BACKGROUND Cryptococcal meningitis (CM) remains a leading cause of death for HIV-infected individuals in sub-Saharan Africa. Improved treatment strategies are needed if individuals are to benefit from the increasing availability of antiretroviral therapy. We investigated the factors associated with mortality in routine care in KwaZulu-Natal, South Africa. METHODOLOGY/PRINCIPAL FINDINGS A pros...
متن کاملClimate Drives the Meningitis Epidemics Onset in West Africa
BACKGROUND Every year West African countries within the Sahelo-Sudanian band are afflicted with major meningococcal meningitis (MCM) disease outbreaks, which affect up to 200,000 people, mainly young children, in one of the world's poorest regions. The timing of the epidemic year, which starts in February and ends in late May, and the spatial distribution of disease cases throughout the "Mening...
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ژورنال
عنوان ژورنال: Nature Medicine
سال: 1996
ISSN: 1078-8956,1546-170X
DOI: 10.1038/nm0596-499a